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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149e8b01f7dec81019ddfe7f3eb6e0f9a8cec6049219de20f5bd1ef3d1642001' 
  AND token = 'z5707BpD5pZNjAqxVVbgq5eNnIuosfxUSvEqXFO4KG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}