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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c641b9144e0eb20067df15ec122711bb39b2d68c99ef1d4c2f799f1af6588052' 
  AND token = 'pawYYQRDfMPqgR2y/SS0KReNNwx4TiSwIftQ2IXHX4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}