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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f7b6527a61d32dfe9ae2212686cfe9f06c34022dc85e7696f70a3b5a452330a' 
  AND token = 'FMi/6myKOb6BoYKNHusiNzE19DeNoahXGmDkIf0tzkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}