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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7c2194164003841499f11c09af301d1f1f798682b6205c34f7c69f8fd77f08' 
  AND token = 'e0kPXronBf9ntr1mAPsTIt5xhxSvtZ8dfa6VvNQMNyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}