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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc59225a4b3efbee24852dedc0abd7f4755afa7383d0fe4c44ade333d05e1b7' 
  AND token = 'Yvp2cpbFYOID6OhmoPYzWK4MqKlK3wi1kpp6AaoC2MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}