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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de16c06cb48d5072f20698c7ad346fef47e6ec5353f36d4dbb4bcf6e91e45a01' 
  AND token = 't2WUYc12en1o9cUmcuGGCwMCI1HjpXnWAiekW3Dbu1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}