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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5857759a8ca206c19d80e25724c0bd14c3a849ab345056708e03308fe0670d04' 
  AND token = 'JBRB+ielRQC6iQ4pw1xg1h4/AEKS2w1YrZUvcPynuOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}