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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3c9e134f41cbcdafe4020e1109435fe22c3eea1972912543964ccdf016d0201' 
  AND token = 'bNB5ZhGQuqYnHrVAWq0pF5B8BXQldb/hLj6Qc1gSPIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}