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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81423cf75fd061070abe153740d802362e79670899c798099f1dd34dc53f20b' 
  AND token = 'Sg/TcDxKHTDYNlRjem1sf2Nh2AtUuiokfhuprKFLyM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}