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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7a65a1fdfb7a7712ac8cdbe5c080f999b55b05b3cd6f70bfec04e684e86298' 
  AND token = '8BygjPGoRVZ2Y17HoTft9uzhnXocdnGLAMd+MDSFnEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}