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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f478a8351c9bd664c6e7c522285122a9c85aa91a5bf713c74d363e6e5e4143' 
  AND token = 'ZPqogX13G1roC8TFuBxrco4uRtQBBqcL0sUcf+Nx+PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}