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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b4c34b187e392bcfa644fea5b3e9389cceece1bf2d8a2ecc2b00d0b4bcacca' 
  AND token = 'z/tLR+6TnEyEmlT+4M74t/76pA4Clp7okLw9zcVd0xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}