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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b365ad98a18ddfd8b2c9acfc053afb1ff9cb7ad85652ea0c15d6568fa78b25' 
  AND token = 'GG7CXIULUXNNDPbj5+LudrXc8lOAITgQbfgPLNIKlLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}