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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab86bee930a37aa1446fa7a82e6f34b2104ec35c8b021d6be7face7f9a466da1' 
  AND token = '50I02o8QuJAX7F1qOWwJDosyyxe3IN8H7FNqfIFZZYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}