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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efcdfcb8a3ec2166e69dc0d50710413236d5cd4ace7aca46f9a4ad78f1a440b' 
  AND token = '2riH6IBV2aL8tzr1Ikld8XDrQnDc5zBM+8x2h5DFIws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}