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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef349b8cecace76d43b6760404fb8984c1421130ad24c56f5a35ff6a0e6a0af' 
  AND token = 'PO6dCiuuPqXaz8bRdiF4Tn4EO2dCkMmyaFaawoWzMbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}