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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5bb3d783a03efe5de43bbc0350cf91cc54f7dcd63b7e4df373b2ffba1300e2' 
  AND token = 'Jc8pYYRZ2W5eI0Sp+F1MHdvo69bB635COJDG/aRhsoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}