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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34fdee3a13f57032421177c810e6a6c6f7b706ab2124c3945be9d8dfebc6be73' 
  AND token = 'vjhSYIuDVpSbHBp/Nt90sByBLOZeJSxYFlk0/pe2Xlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}