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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d465cc17305e34cc73553594116f4351e9a2fe567146213ba199eaf262ea8a' 
  AND token = 'BlQZeV+dOEWYNE2rloPqD0e5CPVaYofeqn03mPMC96E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}