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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd336109f68d5667ca6855f0f9ff3e1d43c9be9e6b71d78adcbff1f3ca8f7e231' 
  AND token = 'clZgPy2df3/taSM+CyIkfiQyxATV7ivYl8tr3PancaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}