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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b144c98a5067afe9d4f7f2af7b5821c36cc6f8c9571e0a7a5c0e61dfec646825' 
  AND token = 'Wiq7y/RARxMm7VzfFPmCHj832All61cnmLco2OByLXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}