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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e424ac9506d215eca79d57ebd204135e5515951cb8e399f998caa826a722e44' 
  AND token = 'y04BK/oAJqWWEvHsI8Gnly+MV8+6gnNSt3esuXXXJIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}