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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de43bba414f7d449e4fe6045ce2db8782a3aeca4c389444bd7c0f58dab9c8a8' 
  AND token = 'OLS6EZ/Dx8fUSumGFqqtvUvt9RGW1Pti453nZ06Zqys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}