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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32e767d911232445a72a4a28398ce20d52376ef514f4e282861c583bd3baf620' 
  AND token = 'hwXAUMIMkSyyBkUg1UIoIkHjBdwBYzEqLDXMxdCmus8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}