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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1516aa2061817b7fb3f71c0f19efa1cea4c4dc548a5491fefd532b3d8259e057' 
  AND token = '3nceipZxxZp4WGHhq05B61f5x9pJv5KxDTKF66OvgV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}