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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081c53e397652366334822ee74497010301658aa3fcd15fb2e8e04dbb3a69ea0' 
  AND token = '17nxL3eSSV5ijnhHgT7bdsl2wLEdWxnfZcBirOkEc+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}