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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b9b29c7ce2373d927339e7d198508cb7bf04aef62d3a749bee957f4b39aa41' 
  AND token = 'vDhjAhSgBpNwoeYR5/5xhyjXwH5kNJoUjL2t3IWAkkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}