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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7617a671c65fe619014d5387f484eeb8cd334431020df56a266151c9a2e8ee2' 
  AND token = 'iTFQWkj5U+QE1OaTewrFpLnehM36yGatpPx5BhGlqGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}