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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a0b03cc1bb544ec0cbddd49c348db5f48e4fe9529c6fe57e4b2ad004ca58d6' 
  AND token = 'Sxd2+l3oqPK5hwNkSC1cvcNC6tucoW/YJpKBmt2XaaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}