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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427f23c7229e067099c288d956db4bcc5d92889c58c3e62c93781364c8f78540' 
  AND token = 'bnIu/uunOMkHjuu3Y/p6JLGsGbBg3tYsjoB/7tamfzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}