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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36276ad9649c8794be5b076c52b2c52017f29c87105ab06175ac15c3bd0860ed' 
  AND token = '1XWsq4Nz5Wwa/pwa5S8dtg0fMBHOJZ/Ni+aU37dSBcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}