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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dccbcec3a11a8c581aa92644f07069ef272e4207ab599b0fe2ddc3d5409a271a' 
  AND token = 'x6NHbu/V39DjJYSRss8VFmyEJmDYDVWGBjfT3GeYe1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}