SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ded57a8e480838fa3b26c3c7feb6f58d54910cb5fd6aca8c62c715b99af019' 
  AND token = 'VcP0I93pMPFthyxgAdoQoASX6cKPxQj+2MwwTNOQLkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}