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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3f0a0e640398d03a3cefac91d36b044fc991b63d5ba5e7fb94bd2cb9988672' 
  AND token = 'MHu0eB8mIKf7FW+WowSrSiGrFFzM3MhZwMfzp4wQVaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}