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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7b3707f9f94722dc4b75c703c238daeb40215766e4bd7e90c4578ffd1c47125' 
  AND token = 'dwN4ySdyiyZ2p3MnElrLpk12rNYn/0SlYZPOma3yaM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}