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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7438cd6efc697f19c1bcd2d1cd0e1223aed8dba8fca2f8ab40933b102331cb26' 
  AND token = 'OPD4v/0+KKjFkWLrXPMiUjyTETVXJF39SKTz7f2WH7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}