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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309428464d7c637a1cbbf48077e8a1b534bb7a0eca5963698a642a05764fb8c2' 
  AND token = 'OWEOaEUquFSeoZ+kD8L9lI92Yb93TA2bfWVKYl+9sH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}