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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd52d7426314fa3730260066a38582e6aadad20647d77bd2d4c50515f76b00eeb' 
  AND token = 'KfgM51xUD6CtYZMd9o72Y2Coj/dDwQBmlAeRH/Gfdws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}