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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e197c2eeed36a3050e26cf27a84836f7af01cc4b52585b500c63f26530757f' 
  AND token = 'gTDygz0oE91i88BjfdTt2izxVW68V8VOJeo5NK0OXHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}