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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f087ad52d028693a4f05493643a6d1d2639cf6188f9fe4eea2e68b1a226514' 
  AND token = 'sAQcosjBM/6/UIlrZXdgTjIi9ranGl1dda5vvwNAuD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}