SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd44449c7c6e633b3ef5660ebfc2043beb2c5e5f94fce8eaca617b6894593fa1e' 
  AND token = 'Yci2ALQ0Nnz2c5oOW2VSCIKnMEtd5LcljbFX3kuetCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}