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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff193ddd4d0ca1b21caa392f305d64a4e64a4617b7e22e0c86c344db58a331a' 
  AND token = 'Ovr69nFJGqRQxKzvmpmlM54tC+K8/Id+GI1mesNL+J4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}