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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab8cfb88895584d9266d54f98e60af0f621e60be8a211febd5299eb02cff067' 
  AND token = 'xs50goyGmSh7ICQq5+5PpqR1XAlg928ps6gmGmdbIFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}