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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e67be32773b8370d8853e3825f266dcc6cea6f3b1c73c1e68a4944a1d61336a' 
  AND token = 'CkIBSR6nIUDOgbkN0GYzHyCeD6uHfVf+aO+GvMQmcho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}