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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '281ee705493e17e23c3a1af415d9a1be5d6d0c9bd5bee29381f979f713e1adc9' 
  AND token = 'fylASxmPwDGRJQm+na9kNYpotQb+x3Wfqdva4XKV9SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}