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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44ce9b8b9be38e21b1179cd78ef20fa8c2b7def385047acf648bd23706cf941' 
  AND token = 'oDbPhPjeV876yPa6Rp3DBJt9yvjkDeIxyMcZ+zI5qcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}