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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7408ac78031006b9c7918ae183dca850384e6f015d8322caa8e870fe6e8561c' 
  AND token = 'O2gHh2DvosLMppZr1suL7jqL5Lr82ZNnRbiNbwLc1cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}