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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88a2c7fe06b090a8df96abdc1c55c24d652583f83d9c1aec708fb30b224d42ab' 
  AND token = 'LRqJn3VElSVnu7h3uwCCLBRDkP0IydQFk3AKPrBitAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}