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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd15aae3d7d82c4d3ebdb55629ee81447c5bf25b220f1d08e9dfdad4230781f5e' 
  AND token = 'wO/niW7N1P2NulVU0Mwogkls03xMpBopUMhR15JkUsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}