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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6ac96f768e8a5aa139761e42a4374ec4df7b64d3144e1cdea34b9253f6efd5' 
  AND token = 'LxvEvmY9StD8v6glu576Xtf1dQ3Ak5JfOVkZzjxXfmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}